Journal of Antivirals & Antiretrovirals
Open Access

Pôle Psychiatrie Santé Mentale Addictologie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg, F- 67091 Strasbourg Cedex, France

Publications

• Research Article   
  Impact of Direct-acting Antivirals on Hepatitis C Cascade of Care among People who Inject Drugs
  Author(s): Doffoel Michel*, Di Nino Fiorant, Chaffraix Frédéric, Lang Anais and Lalanne-Tongio Laurence
  
  In France, the care pathway for PWID is not straightforward, even among prevention and treatment addiction centres. The aim of this study was to describe and compare the HCV cascade of care in PWID patients followed up in such centres from 2012 to 2017, namely before the 2014 era of interferon-based treatment until the 2014 advent of DAA therapy onwards. The study included an educational component, along with the setting up of a care pathway with an integrated and multidisciplinary approach. 1054 PWID were evaluated, 242 from the interferon-based treatment period and 812 from DAA. Poly-addiction was common, mainly including tobacco (88%) and alcohol consumption (54%). Among the PWID, 77% were screened for anti-HCV, with 34% of them being positive. Besides, 75% of PWID positive for anti-HCV were tested for RNA-PCR, with 68% of them being positive. Among the 140 PWID with HCV infection,.. View More»
  

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