Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
Department of Dermatology, University of Malaga, Malaga, Spain
Commentary
Note on Benefits of Retinoid for Skin
Author(s): Kenneth Jones*
Retinoids reduce fine lines and wrinkles by increasing the production of collagen. They also stimulate the assembly of new blood vessels in the skin that improves skin colour. Additional benefits include fading age spots and softening rough patches of skin. Vitamin A and its derivatives, notably retinol slows both chronological and photo-induced aging processes. Retinol reduces the appearance of wrinkles and therefore they decrease the skin firmness and elasticity property by protective against scleroprotein and elastin fiber changes [1]. Additionally to retinol’s rejuvenating skin advantages through direct transcriptional activation, recent study suggest an epigenetic regulation through micro-RNAs (miRNAs) modulation. We investigated how retinol supports the stimulation of Type I scleroprotein and elastin through proteomic, transcriptomic and epigenetic miRNA-expression changes.. View More»