ISSN: 2471-9315
School of Basic Medicine and Life Sciences, Hainan Medical University, Hainan, China
Research Article
Greatest Common Divisor Deciphered SARS-CoV-2 Superpandemic
Author(s): Ke Jia Dong* and Wen Hua Li
Global cases and deaths showed that COVID-19 and 1918 influenza were not normal pandemics, but superpandemics. Was there a common mechanism to push pandemics into superpandemics? This common ground was explored here from a new perspective and approach using the Greatest Common Divisor (GCD). The results showed that superpandemic viruses played tricks like superbugs. One subtlety was that SARS-CoV-2 fighted antibodies, just as superbugs fighted antibiotics. The SARS-CoV-2 spike and ORF8 proteins recognized the “Achilles heel” of secretory antibodies, namely J-chains and secretory components, and hijacked them respectively. Another subtlety was that SARS-CoV-2 expanded ORF8 protein as a superpandemic catalyst, just as drug-resistant enzyme facilitated the spread of superbugs. The SARS-CoV-2 ORF8 protein corresponded to the 1918 H1N1 virus neuraminidase. Both funct.. View More»
DOI:
10.35248/2471-9315.23.9.244