Journal of Clinical Trials

Journal of Clinical Trials
Open Access

ISSN: 2167-0870

Kazumi Fujioka

Department of Radiology, Nihon University School of Medicine, Tokyo, Japan

  • Review Article   
    Association between Chronic Liver Disease and Atherosclerosis: An Inflammation as Common Pathway
    Author(s): Kazumi Fujioka*

    Atherosclerosis status as an inflammatory disease has been suggested and anti-inflammatory therapy with canakinumab for atherosclerotic disease has been recently reported. The author previously described the relationship between APRI (aspartate aminotransferase to platelet ratio index) and endothelial function assessed by Flow-Mediated Vasodilation (FMD), thereby suggesting that APRI may reflect systemic atherosclerosis condition in elderly patients without hepatic-related causes. Some reports of the relationship between NAFLD/NASH and atherosclerosis status and between chronic Hepatitis C Virus (HCV) infection and atherosclerotic state have been described. As both chronic liver disease and atherosclerosis involve severe inflammatory processes, at least common pathway may be present for the development and treatment of these inflammatory diseases. The current knowledge of the relation.. View More»
    DOI: 10.35248/2167-0870.21.11.444

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