Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
National Skin Centre, Mandalay Road, Singapore
Research Article
Antibiotic Sensitivity of Cutibacterium acnes Isolates from Acne Patients
in a Skin Hospital in Singapore
Author(s): Aditi Jha*, Timothy Barkham, Siew Pang Chan, Audrey WH Tan, Mark BY Tang, Hiok Hee Tan, Mark JA Koh, Shang-Ian Tee and Virlynn Tan
Background: The increasing use of antibiotics for acne has led to the development antibiotic resistant propionobacteria and has become a worldwide problem in the recent years.
Objective: We investigated the prevalence and pattern of antibiotic resistance to Cutibacterium acnes (C. acnes) and its relation to previous antibiotic therapy in acne patients attending the dermatology outpatient clinic in a tertiary dermatological referral Centre in Singapore.
Methods: Skin swabs were collected from the skin lesions in 402 acne patients at baseline, 2months and 4 months. Cultures for C. acnes were done and sensitivity testing of the isolates was done using 5 commonly used antibiotics, namely tetracycline, minocycline, doxycycline, erythromycin and clindamycin. Data was collected about the previou.. View More»