Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
ISSN: 2161-0495
Clinical Pharmacology and Toxicology Unit, Schneider Children’s Medical Center, Petah Tiqva, Israel
Case Report
Neurologic Involvement in a Young Child with Paraquat Poisoning Treated with Rapamycin
Author(s): Inbar Zioni*, Adi Glass, Yedidia Bentu, Patrick Stafler, Liora Kornreich, Gilat Livni and Havazelet Yarden-Bilavski
Parquet (1, 1’-dimethyl-4-4’-bipyridinium dichloride), an agricultural herbicide, is highly toxic to humans. A 78% mortality rate previously reported for the ingestion of 20% Paraquat commercial preparation. No specific antidote is available; hence cases of poisoning require aggressive decontamination. We report an unintentional ingestion of a 15- months-old male who developed severe neurologic manifestations. Clinical experiences were seen; in vitro and animal models often demonstrate a lack of consistency with clinical response... View More»
DOI:
10.35248/2161-0495.21.11.493