Journal of Antivirals & Antiretrovirals
Open Access
ISSN: 1948-5964
ISSN: 1948-5964
Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran, Iran
Research Article
Another Step Toward Final Call on Remdesivir Efficacy as a Treatment for Hospitalized COVID-19 Patients: A Multicenter Open-Label Trial
Author(s): Hamed Hosseini, Anahita Sadeghi, Payam Tabarsi, Azin Etemadimanesh, Ilad Alavi Darazam, Nasser Aghdami, Saeed Kalantari, Mehrdad Hasibi, Azar Hadadi, Farhang Babamahmoodi, Mansooreh Momen-Heravi, Ahmad Hormati, Yunes Panahi, Rozita Khodashahi and Mohammadreza Salehi*
Objective: After emerging the global pandemic of SARS-CoV2 some preliminary studies demonstrated the efficacy
of antiviral treatments. But shortly thereafter, inconsistencies in the results of further clinical trials raised doubts on
the efficacy of these agents. In this study, we aimed to evaluate the effect of Remdesivir on hospitalized COVID-19
patients’ outcomes.
Materials and methods: This study was an open-label, single-armed, clinical trial on hospitalized patients diagnosed
with COVID-19 who had progressive respiratory symptoms despite receiving standard care. All patients received
Remdesivir and their characteristics, outcomes, time of treatment initiation, and respiratory support stages during
hospitalization were registered and followed up for 14 days.
Results: 145 patients with the m.. View More»
DOI:
10.35248/1948-5964-22.14.002