Journal of Hematology & Thromboembolic Diseases
Open Access
ISSN: 2329-8790
ISSN: 2329-8790
Department of Hematology, Madras Medical College, Chennai, India
Research Article
Impact of Preoperative Anemia and Blood Transfusion on Long-Term Survival Outcomes in Colorectal Cancer Surgery
Author(s): Gupta Abhishek*
Background: Perioperative anemia and blood transfusion are closely intertwined factors, exerting adverse effects on the survival outcomes of Colorectal Cancer (CRC) patients. Despite prevailing reliance on transfusion for anemia treatment in several countries, questions persist regarding the combined impact of preoperative anemia and postoperative anemia, as well as preoperative anemia and blood transfusion, on the long-term outcomes of CRC patients.
Methods: A retrospective propensity-score-matched analysis was conducted on 100 CRC patients undergoing elective surgery between January 1, 2022 and December 31, 2023. Novel models were constructed using Kaplan-Meier survival analysis and univariable and multivariable Cox proportional hazards models, following propensity-score matching. Prognostic factors for Overall Survival (OS) and Disease-Fr.. View More»