Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
Medical Department, Cantabria Labs Difa Cooper, Milano, Italy
Research Article
In vivo Assessment of Hydration, Skin Barrier Function, and Redness Reduction of a Cosmetic Cream Formulation Containing Vitamin B 12, Folic Acid and Red Algae Extract (Jaluronius B Complex) in Subjects with Sensitive Skin and Moderate Skin
Author(s): Stefano Alfano, Francesca Colombo and Massimo Milani*
Background: Sensitive skin is characterized by reduced barrier integrity, increased Transepidermal Water Loss (TEWL), and proneness to irritation and redness. Cosmetic formulations targeting hydration and barrier repair can improve comfort and visible skin condition.
Objective: This study aimed to assess, in vivo, the moisturizing, soothing, and barrier-protecting efficacy of a cosmetic formulation in cream formulation (Jaluronius B complex, Cantabria labs Difa Cooper) in female volunteers with sensitive skin and mild to moderate skin ageing.
Methods: A single-center, open-label, randomized intra-individual (half-face) controlled study was performed on 20 healthy female volunteers aged 21-45 years. The tested product was applied twice daily for 6 weeks to one side of the face, while a neutral base cream served as the control on the contralateral area. Stratum corne.. View More»