Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
ISSN: 2161-1017
Anatomy Department, Faculty of Basic Medical Sciences, College of Health Sciences, Osun State University, Nigeria
Research Article
Diabetes and Its Complication: Aqueous Leaf Extract of Alafia barteri Maintained the Pancreatic and Gastric Integrity in Allosan Induced Diabetic Rats (Rattus novergicus)
Author(s): Adeeyo Olusola Atilade, Fakile Adedoyin Ruth, Ekunseitan Olawunmi Magret, Dare Babatunde Joseph, Ojo Waliu Adetunji, Ebiwonjumi Adetunji Segun and Okeniran Olatayo Segun
Alafia barteri, Apocynaceae has been valued for its efficiency in traditional medicine system in Nigeria and other African countries, as an anti-inflammatory and fever remedy. This study was carried out to know the effect of Alafia barteri leaf extract on the histo-architecture of the pancreas and stomach in Alloxan induced diabetic wistar rats.
A total of Twenty (20) Wistar rats were used for this study, animals were randomly selected into Four (4) groups of Five (5) animals and were acclimatized for period of Two (2) weeks Group 1 the Control Group (CG) received 2mls of distilled water, Group 2 Normoglycemic Treated (NT) with 400 mg/kg of Alafia barteri aqueous leaf extract, Group 3 Induced Hyperglycaemic Untreated (IU), and Group 4 Induced Hyperglycaemic Treated (IT) with 400 mg/kg of Alafia barteri aqueous leaf extract. Hyperglycaemic .. View More»