Journal of Developing Drugs

Journal of Developing Drugs
Open Access

ISSN: 2329-6631

+44 20 3868 9735

Dinesh Sharma

Department of Pharmaceutical Science, Roorkee College of pharmacy, Uttarakhand, India

  • Research Article   
    Formulation and Evaluation of Mouth Dissolving Tablets Prepared by Micronized Terbutaline Sulfate and Using Co-processed Superdisintegrants by Direct Compression Method
    Author(s): Dinesh Sharma*, Rajesh Aggarwal and Rajeev Tomar

    The present work contains details of formulating and evaluation of mouth dissolving tablets of micronized terbutaline sulphate by using co-processed superdisintegrants and taste masking agent (flavors and ion exchange resin) with an aim to get a dosage form having fast disintegration. Terbutaline sulphate first pass through size reduction technique which leads to increase in surface area and increased in oral absorption of the drug. As a part of pre-formulation study, the physicochemical compatibility study of the drug with different excipients was done and drug-excipient interaction was assessed from thermal analysis by using differential scanning calorimetry indicated absence of interactions between the selected excipients for the study. Moisture absorption study of the drug indicated that the drug is non-hygroscopic. Thermal (stress) Stability of the dr.. Read More»
    DOI: : 10.35248/2329-6631.22.11.179

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