Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Homi Bhabha National Institute, Bhabha Atomic Research Centre, India
Research
Influences of Formalin Gas on Gene Expression Level of Tumor Protein TP53 in the Liver and Kidney of the Quail (Coturnix coturnix)
Author(s): Dharmendra Kumar Maurya
This study was the first to highlight the deleterious effect of formalin gas on gene expression of the tumor protein TP53 in the liver and kidney. This experiment was conducted according to the animal ethics and regulations of the college of veterinary medicine and the University of Al-Qadisiyah. Quails were divided into four groups: Three groups were exposed to two hours of formalin gas twice daily, two hours in the morning and evening, for 30 days and the fourth group was the control with the same environmental conditions except for formalin. Then, quails were killed on different days (10, 20 and 30 days) and liver, kidney and blood specimens were collected for gene expression, histological and biochemical studies. The result displayed that formalin gas caused by disturbances in liver and kidney functions, in addition to the great pathological liver and kidney changes, showed acute .. View More»