Journal of Antivirals & Antiretrovirals

Journal of Antivirals & Antiretrovirals
Open Access

ISSN: 1948-5964

Bikram Dhara

Post Graduate Department of Microbilogy, St. Xavier’s College (Autonomous), Kolkata, India

  • Review Article   
    A Review on the SARS-CoV-2 Mediated Global Pandemic: Proximal Origin, Pathogenicity and Therapeutic Approaches
    Author(s): Soumi Chatterjee, Bikram Dhara*, Dattatreya Mukherjee, Debraj Mukhopadhyay and Arup Kumar Mitra

    The world is amidst a public health crisis as the pandemic has shook us to the core. The COVID-19 caused by the novel SARS-CoV-2 is of zoonotic origin and this tries to explain what could have been the possible proximal origins for the disease in humans. Our review aims at addressing the question like what structural or genomic vicissitude enabled the viral outbreak across genera and so efficiently infect the human populace across the globe. We also try to discuss the prospect of drug repurposing and scope for vaccine development considering the rapid genome modification of the virus. Another finding lies into the action of pre-existing drugs when they are applied in combination and probably that shades some light on the therapeutic approaches. Several investigations have been performed but we are still in search of a novel antiviral drug. With that vision, our fo.. View More»
    DOI: 10.37421/1948-5964.21.13.220

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