Immunome Research
Open Access

Department of Biomedical and Surgical Sciences, Section of Ophthalmology, University of Perugia, S. Maria Della Misericordia Hospital, Perugia, Italy

Publications

• Case Report   
  Incomplete Macular Hole Closure after Human Amniotic Membrane Plug Transplantation: Is Sulfur Hexafluoride Reinjection Necessary?
  Author(s): Tito Fiore*, Davide Tucci, Greta Castellucci, Barbara Iaccheri, Marco Lupidi and Carlo Cagini
  
  Purpose: To report a case of a patient with a Full-Thickness Macular Hole (FTMH) treated with a Pars-Plana Vitrectomy (PPV) and the positioning of a human Amniotic Membrane (hAM) plug. Methods: Patient was surgically treated with PPV, hAM plug implantation and SF6 (sulfur hexafluoride) as endotamponade. A complete ophthalmic examination and an Optical Coherence Tomography (OCT) were performed at every visit. Results: After surgery, the edges of hAM were elevated, folded and not perfectly outspread under the surrounding retinal layers, which were thickened and elevated, due to the presence of a persistent intraretinal oedema. A new surgery with reinjection of 20% SF6 was performed, but despite the closure of MH, neurosensory retina migration over the hAM plug was incomplete and macular edema persisted. Conclusion: hAM transplant is a valuable option for MH surgery. Plug dimension shoul.. View More»
  

  Abstract PDF