ISSN: 2155-9880
Department of Medicine, São Paulo State University, Botucatu, Brazil
Mini Review
Therapeutic Potential of Pera Orange and Moro Orange in Cardiac Remodeling by Cardiovascular Diseases: A Metabolomics Approach
Author(s): Anderson S.S. Fujimori, Bertha Furlan Polegato and Priscila Portugal dos Santos*
Cardiovascular diseases is a leading cause of death worldwide and the process of cardiac remodeling lies at the core of most of these diseases. The sustained cardiac remodeling almost unavoidably ends in progressive muscle dysfunction, heart failure and ultimately death. Therefore, in order to attenuate cardiac remodeling and reduce mortality, different therapies have been used, but it is important to identify adjuvant factors that can help to modulate this process. One of these factors is inclusion of affordable foods in the diet having potential cardio protective properties. Study carried out by Fujimori, et al. showed that ingestion of pera and moro orange juice induces changes in plasma metabolites related to the regulation of extracellular matrix, inflammation, oxidative stress, and membrane integrity in healthy rats. Additionally, the review of the metabolic pathways related to .. View More»
DOI:
10.35248/2155-9880.25.16.946