Journal of Antivirals & Antiretrovirals

Journal of Antivirals & Antiretrovirals
Open Access

ISSN: 1948-5964

+44 1300 500008

Ali Hasab

Department of Epidemiology, High Institute of Public Health, Alexandria, Egypt

  • Research Article   
    Non-Randomized Clinical Trial to Interrupt Vertical Hepatitis B Viral Infection
    Author(s): Khaled A. Abu Ali*, Ali Hasab, Noha Awad and Yehia Abed

    Background: Hepatitis is an inflammation of the liver, can be self-limiting or progress to fibrosis, cirrhosis, or hepatocellular carcinoma, HB occurs as a result of parenteral contact with infected body fluids, could be vertical from mother to baby or horizontal. Aim of the study: To assess the effectiveness of HB vaccine alone versus HBIG combined with HB vaccine in the interruption of neonatal HB viral infection. Methods: A Non-randomized clinical trial was conducted, 228 subjects distributed into two groups, the control group: newborns of mothers with inactive HBV infection were given HBIG and HB vaccine and, the intervention group: Newborns of mothers with inactive HBV infection were given HB vaccine alone. Results: showed that the two immunization regimens were effective in.. View More»
    DOI: 10.35248/1948-5964.21.s20.003

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