Biochemistry & Pharmacology: Open Access

Biochemistry & Pharmacology: Open Access
Open Access

ISSN: 2167-0501


Yogesh Chand Yadav

Yogesh Chand Yadav
Pharmacy College Saifai,
Saifai-206130, Etawah, UP

  • Research Article
    Effect of Ficus benghalensis L. Latex Extract (FBLE) on Cisplatin Induced Hypotension and Renal Impairment in Wistar Rats
    Author(s): Yogesh Chand YadavYogesh Chand Yadav

    Background and objective: Ficus benghalensis is a remarkable tree that sends down its branches and great number of shoots. It is used for treatment of neuralgia, rheumatism, lumbago, bruises, nasitis, gonorrhoea, inflammations, cracks of the sole and skin diseases and in ayurveda for diarrhea, dysentery, and piles”. To evaluate protective activity of F. benghalensis latex extract (FBLE) on cisplatin induced hypotension and renal impairment in wistar rats. Materials and methods: Rats were divided five groups and duration study 16 days. 1st group administered 5 ml/kg normal saline; 2rd group FBLE treated group 400 mg/kg per day; 3rd group (cisplatin treated) with single dose of cisplatin (5 mg/kg, i.p.) on 1st day and keep animals up to 6 days; 4th Group and 5th Group FBLE treated (200 and 400 mg/kg, p.o.) of for 1st to 10th day and single dose of cisplatin (5 mg/kg, i.p.) on 11t.. View More»
    DOI: 10.4172/2167-0501.1000216

    Abstract PDF

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