ISSN: 2157-7048
+44-77-2385-9429
Yang Zhang
Tanzania
Research Article
On Improved Mechanistic Modeling for Enzymatic Hydrolysis of Cellulose
Author(s): Yang Zhang and Wen ZhouYang Zhang and Wen Zhou
An improved model for enzymatic hydrolysis of cellulose is developed that considers oligomer reactions with beta-glucanases, inhibition of oligomers to cellulases and enzyme decay processes during hydrolysis. Our oligomer reactions with beta-glucanases are modeled based on the enzymatic glucan chain fragmentation kinetics to describe the further fragmentation of oligomers in solution after being solubilized from the insoluble glucan chains. The inhibition effects on all cellulases by different types of cello-oligomers are then taken into account by competitive adsorption of cello-oligomers to the active site of cellulases, which is a critical factor contributing to the decrease in the rate of enzymatic hydrolysis of cellulose. As another factor affecting the kinetics of cellulose hydrolysis process, enzyme decay factor is incorporated into the model as the typical first order decay pr.. View More»
DOI:
10.4172/2157-7048.1000190