Journal of Medical Diagnostic Methods
Open Access
ISSN: 2168-9784
ISSN: 2168-9784
Sten Dreborg
Women's and Children's Health Academic Hospital,
Uppsala
Sweden
Review Article
Evaluation of Skin Reactivity: The concept of Histamine Equivalent Allergen Threshold Concentration (Cha)
Author(s): Sten DreborgSten Dreborg
Background: Skin prick testing is the most common diagnostic tool used by allergists. There are limited, international rules on interpreting and reporting skin test results in a meaningful way.
Aim: This communication describes methods to express the results of skin prick tests in a meaningful way. It is recommended to use allergen extracts with defined composition, potency and stability, to keep the precision of SPT within acceptable limits by using duplicate tests, and to regularly calculate the c.v. If duplicate tests cannot be performed for practical and or psychological reasons, e.g. in small children, then it are proposed that regular proficiency tests are performed and reported. The method of estimating the allergen threshold concentration, histamine equivalent allergen concentration Cha, is described
Conclusion:.. View More»
DOI:
10.4172/2168-9784.1000242