Journal of Applied Pharmacy
Open Access

Sivakumar T

Publications

• Research Article
  Antimicrobial Activity of Flavone Analogues
  Author(s): Kamlesh KN, Sivakumar T and Afroze AKamlesh KN, Sivakumar T and Afroze A
  
  Background: Most of the available antimicrobial drugs have developed resistance; some of them suffer from severe toxicity, side effects. So, there is a need to discover novel compound(s) which should not only be potent, but also less toxic and cost effective. Objectives: The aim of the study is to develop new synthetic antimicrobial agents (Anti-bacterial and anti-fungal) such as 3-substituted flavone/flavanone derivatives, which should be significantly potent with low toxicity. Method: An attempt was made to synthesize a newer series of 3-methyl flavanone derivatives together with the synthesis of a series of 3-hydroxyl flavone analogues. The structures of the test compounds were elucidated and established by UV, IR, H-NMR1, C-NMR13 and mass spectrometry. The synthesized compounds were subjected for in vitro antim.. View More»
  DOI: 10.21065/1920-4159.1000232

  Abstract PDF

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