Journal of Medical Diagnostic Methods
Open Access
ISSN: 2168-9784
+44 1300 500008
ISSN: 2168-9784
+44 1300 500008
Shewatatek Gedamu
Institute of Health sciences,
Pharmacy, Gibe street, Jimma, Oromia 251
Ethiopia
Review Article
Comparative Evaluation of Treatment for Multi drug Resistant Tuberculosis with and without Surgical Resection: A Systematic Review–Meta Analysis of Retrospective Clinical Data
Author(s): Tewodros Shigute, Shewatatek Gedamu, Andualem Tesfaye, Tewodros Gebremariam, Abdulkerim Dedefo, Mulualem Tadesse, Tesfamichael Alaro and Getnet YimerTewodros Shigute, Shewatatek Gedamu, Andualem Tesfaye, Tewodros Gebremariam, Abdulkerim Dedefo, Mulualem Tadesse, Tesfamichael Alaro and Getnet Yimer
Background: Tuberculosis is still one of the major causes of mortality and morbidity in the world with nearly 1.3 million deaths recorded in 2012. Multi drug resistant tuberculosis has caused high number of deaths and new infections in the same year. The optimal management of MDR TB has been retarded by lack of controlled trials to indicate a fixed drug regimen to be applied universally. Surgical resection, often involving lobectomy and pneumoctomy, is used in patients failing to show improvements with the drug therapy.
Objective: To conduct systematic review meta-analysis on comparative evaluation of treatment for MDR TB with and without surgical resection.
Methods: Eligible studies were identified from databases using key phrases MDR TB, MDR TB treatment, and clinical outcomes for MDR TB therapy. Statistical anal.. View More»
DOI:
10.4172/2168-9784.1000243