Lupus: Open Access
Open Access

Peter Klein-Weigel

Publications

• Short Communication
  Immunoadsorption in Buergers Disease (Thromboangiitis Obliterans): A Promising Therapeutic Option: Results of a Consecutive Patient Cohort Treated in Clinical Routine Care
  Author(s): Peter Klein-Weigel, Theresa Sophia Volz, Beate Gutsche-Petrak, Joana M. Boehnlein, Anne Bohlen, Siegrid Dreusicke, Jana Valerius, Marion Bimmler, Petra Hempel, Leonora Zange, Sebastian Schopp and Saban ElitokPeter Klein-Weigel, Theresa Sophia Volz, Beate Gutsche-Petrak, Joana M. Boehnlein, Anne Bohlen, Siegrid Dreusicke, Jana Valerius, Marion Bimmler, Petra Hempel, Leonora Zange, Sebastian Schopp and Saban Elitok
  
  Background: Buerger`s disease (TAO, thrombangiitis obliterans) is an inflammatory vessel disease affecting small and medium sized arteries and veins leading to acral or limb-threatening ischemia syndromes and/or thrombophlebitis with high amputation rates. Immunhistopatholocical and serological data let to the new paradigm of an immunopathogenesis of TAO. Based on this hypothesis immunadsorption (IA) was successfully introduced into the therapeutic spectrum and the presence of G-protein coupled autoantibodies in TAO and their successful elimination by IA was shown. Objective: We present an update of the results of our observational cohort study including patients suffering from TAO consecutively treated by IA in clinical routine care. Patients and methods: From December 2012 to February 2016 twenty-two patients suf.. View More»
  DOI: 10.35248/2684-1630.16.1.114

  Abstract PDF

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