Lupus: Open Access
Open Access
ISSN: 2684-1630
+44 1300 500008
ISSN: 2684-1630
+44 1300 500008
Martin-Gomez MA
Nefrología, Hospital de Poniente,
El Ejido, Almería
Spain
Research Article
Malaga Study: 25 Year Background in Lupus Nephritis in South of Spain
Author(s): Martin-Gomez MA, Frutos Sanz MA, De Ramon Garrido E, Camps Garcia T, Valiente Sanchis L, Valera Cortes A, Fernandez Nebro A, Garcia Gonzalez I and Toledo Rojas RMartin-Gomez MA, Frutos Sanz MA, De Ramon Garrido E, Camps Garcia T, Valiente Sanchis L, Valera Cortes A, Fernandez Nebro A, Garcia Gonzalez I and Toledo Rojas R
Kidney disease has influenced the prognosis of patients with systemic lupus erythematosus (SLE). Fortunately better strategies and new immune-suppressants in the last decades have improved renal and survival prognosis. To study the patient and renal survival and prognostic factors in a cohort of 144 patients with severe lupus nephritis (LN) over a 25-year period at three Southeast Spain centres. We undertook a retrospective analysis of four groups related to time and kind of induction and maintenance treatment. Group A (1985-1990:24 monthly ivcyclophosphamide [ivCyP]); Group B (1991-2000:6 monthly +18 quarterly ivCyP); Group C (2001-2004: fortnightly ivCyP) plus azathioprine [AZT] or mycophenolic acid [MA]; Group D (2005-2010: MA). The whole time of following was 124±86 m. In the first two years, a successful complete or partial response rate was experienced in 92 (77%) without.. View More»
DOI:
10.35248/2684-1630.16.1.103