International Journal of Physical Medicine & Rehabilitation
Open Access
ISSN: 2329-9096
+44 1300 500008
ISSN: 2329-9096
+44 1300 500008
Jun Ni
China
Research Article
Physiologic Remote Ischemic Training Offers a Cardioprotective Effect
against Myocardial Infarction in a Time-Dependent Manner
Author(s): Jun Ni, Qingyun Peng, Chengyao Mei, Minhui Jiang, Xiao Lu, Jianan Li and Jianhua ZhuJun Ni, Qingyun Peng, Chengyao Mei, Minhui Jiang, Xiao Lu, Jianan Li and Jianhua Zhu
Aims: The aim of this study was to investigate the effectiveness of Physiologic remote ischemic training (PRIT) to second MI and the difference of variable durations of PRIT against myocardial infarction.
Methods: A myocardial infarction model was first established in 64 male Sprague-Dawley (SD) rats, and after one week the modeled animals were equally randomized into two groups: the PRIT group, which was further divided into1-, 2-, 4- and 6-week PRIT subgroups as 1w, 2w, 4w and 6wPRIT, and the pure myocardial infarction group, which were further divided into 1-, 2-, 4- and 6-week myocardial infarction groups as 1wMI, 2wMI, 4wMI and 6wMI as controls.. At the end of scheduled time points, all rats received the second MI. Myocardial infarct size, vascular endothelial growth factor (VEGF), capillary density and were determined.
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DOI:
10.4172/2329-9096.1000430