Journal of Medical & Surgical Pathology
Open Access
ISSN: 2472-4971
+44 1223 790975
ISSN: 2472-4971
+44 1223 790975
John V Groth
Tanzania
Case Series
Testis Morphologic Assessment in Patients undergoing Sex Reassignment Surgery with Gender Dysphoria: Case Series and Literature Review
Author(s): Erica R Vormittag-Nocito, Nasma K Majeed, Manmeet Singh and John V GrothErica R Vormittag-Nocito, Nasma K Majeed, Manmeet Singh and John V Groth
Purpose: To study the morphologic changes to testicular architecture in response to estrogen therapy in gender dysphoric patients undergoing sexual reassignment surgery.
Materials and methods: A retrospective morphologic review of testicular architecture was performed on ten cases of male-to-female sex reassignment surgery testis from the University of Illinois Hospital and Health Sciences system. Cases were from adult males undergoing sexual reassignment surgery at the University of Illinois Hospital and Health Sciences System between 2016 and 2017. Architectural changes were measured including Leydig cell changes, basement membrane fibrosis, spermatogonia maturation, and interstitium changes.
Results: Various stages of maturation and regression were seen despite all patients being on estrogen therapy fo.. View More»
DOI:
10.4172/2472-4971.1000172