International Journal of Physical Medicine & Rehabilitation
Open Access

Invernizzi M

Publications

• Research Article
  Safety of Intra-Articular Oxygen-Ozone Therapy Compared to Intra-Articular Sodium Hyaluronate in Knee Osteoarthritis: A Randomized Single Blind Pilot Study
  Author(s): Invernizzi M, Stagno D, Carda S, Grana E, Picelli A, Smania N, Cisari C and Baricich AInvernizzi M, Stagno D, Carda S, Grana E, Picelli A, Smania N, Cisari C and Baricich A
  
  Objective: Osteoarthritis (OA) is a chronic degenerative musculoskeletal disease and one of the leading causes of chronic musculoskeletal pain, often affecting the knee. Despite intra-articular (IA) injectable hyaluronan (HA) preparations are widely used in the treatment of this debilitating condition, only a few data about their efficacy have been reported so far. Therefore, the use of HA in OA management is not universally recommend in clinical practice. Oxygen-ozone (O2O3) therapy can be employed in several pain-related conditions and diseases. However, both its efficacy and safety for IA therapy in knee OA have never been explored. Here, we evaluated the reliability of knee IA therapy with O2O3 compared to IA HA in chronic knee OA. Methods: A total of 42 consecutive chronic OA patients with rad.. View More»
  DOI: 10.4172/2329-9096.1000385

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