Internal Medicine: Open Access
Open Access

Hua-li Wang

Publications

• Case Report
  Case Report of an Unusual Stroke-like Creutzfeldt - Jakob disease with Medulla Oblongata Motor Nuclei Lesion
  Author(s): Cheng-fang Huang, Xi Chen, Dan Jiang, Hua-li Wang, Hong-hua JIN, Wei Yang, Jun Peng, Jie Liu and Hong Zhang  Cheng-fang Huang, Xi Chen, Dan Jiang, Hua-li Wang, Hong-hua JIN, Wei Yang, Jun Peng, Jie Liu and Hong Zhang 
  
  Background: The reports of long-term imaging traces for sporadic Creutzfeldt–Jakob disease (sCJD) have been rare to date, although diffusion-weighted imaging (DWI) has high sensitivity and specificity in the diagnosis of sCJD in the early stage of disease. And sCJD-associated neuropathologic brainstem abnormalities on DWI are considered uncommon. Here, we provided a sequential neuroimaging of a late-onset sCJD with medulla oblongata motor nuclei lesion. Case presentation: We report the case of a 77-year-old woman who presented a typical late-onset sCJD clinical manifestation including rapidly progressive dementia, ataxia, and myoclonus, except vision loss. 14-3-3 protein of CSF was found to be positive, blood gene test detected that the polymorphism at codon 129 was M/M subtypes, genotyping the human prion protein gene (PRNP) did not reve.. View More»
  DOI: 10.4172/2165-8048.1000218

  Abstract PDF

Relevant Topics