Internal Medicine: Open Access
Open Access
ISSN: 2165-8048
+44 1300 500008
ISSN: 2165-8048
+44 1300 500008
Hiroshi Bando
Tokushima University /Medical Research,
Tokushima
Japan
Research Article
Investigation of Elevated Ketone Bodies in Low Carbohydrate Diet (LCD)
Author(s): Hiroshi Bando, Ebe K, Tetsuo Muneta, Masahiro Bando and Yoshikazu YoneiHiroshi Bando, Ebe K, Tetsuo Muneta, Masahiro Bando and Yoshikazu Yonei
Background: Discussion has been continued concerning Calorie Restriction (CR) and Low Carbohydrate Diet (LCD). For years, authors have investigated LCD associated with lipids, renal function and Ketone Bodies (KB) for clinical application of super LCD formular meal. In this study, 3-hydroxybutyric acid (3-OHBA) and acetoacetic acid (AcAc) was measured.
Subjects and Methods: The subjects were 105 patients with type 2 diabetes mellitus (T2DM), (M/F 47/58, 62.7 years. in average) they were admitted for treatment of T2DM. The protocol consists of 3 steps. 1. Calorie Restriction (CR) diet was given on day 1 and 2 with 60% of carbohydrates. 2. Low Carbohydrate Diet (LCD) was given after day 3 with 12% of carbohydrates which is super-LCD formula meal. 3. Total ketone bodies (T-KB), 3-OHBA and AcAc were measured, and investigated the value and ratio.. View More»
DOI:
10.4172/2165-8048.1000260