Journal of Women's Health Care
Open Access
ISSN: 2167-0420
+44-7360-538437
ISSN: 2167-0420
+44-7360-538437
G. Kirtschig
Centre of Evidence Based Dermatology,
Kingâs Meadow Campus, Lenton Lane, Nottingham, NG7 2NR
Research Article
A Dutch Cohort Study Confirms Familial Occurrence of Anogenital Lichen Sclerosus
Author(s): G. Kirtschig and D. J. KuikG. Kirtschig and D. J. Kuik
Background: Lichen sclerosus is a chronic inflammatory disease mainly affecting the anogenital site chiefly in postmenopausal women with an increased risk of anogenital cancer. Its aetiology is unknown; evidence is accumulating that genetic factors increase the risk of LS in families.
Objective: To evaluate the familial occurrence of anogenital lichen sclerosus in a cohort of Dutch individuals with lichen sclerosus.
Method: To evaluate the familial occurrence of genital LS a questionnaire was given to individuals with confirmed LS attending an annual LS meeting asking for LS in family members with an option of a “certain”, “likely”, “not known”, “definitely not” diagnosis of LS.
Results: One hundred and seventeen of 170 individuals returned .. View More»
DOI:
10.4172/2167-0420.1000209