Internal Medicine: Open Access
Open Access

Beenken AE

Publications

• Review Article
  New Drug Therapies for Systemic Lupus Erythematosus: A Systematic Review
  Author(s): Beenken AEBeenken AE
  
  From the literature research the belimumab studies were the only ones to meet the primary and some of the secondary endpoints. Introduction: Systemic Lupus Erythematosus (SLE) is a multiorganic autoimmune disease caused by an immune reaction against DNA. Despite continuous research progress, the mortality of SLE patients is still 2?4 times higher than the healthy populations and the standard drugs’ adverse effects (especially corticosteroids) hamper the patients’ quality of life. That is why there is an urgent need for new therapies. This paper reviews all phase III clinical trials of new SLE medication that were published since 2011 and analyses the drugs for their respective effects. Methods: MEDLINE (PubMed), Livivo, The Cochrane Library and Embase were systematically searched for relevant publications. Only randomized, placebo-controlled and .. View More»
  DOI: 10.4172/2165-8048.1000268

  Abstract PDF

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