Internal Medicine: Open Access

Internal Medicine: Open Access
Open Access

ISSN: 2165-8048

Barber TM

Barber TM
Warwick Medical School,
Clinical Sciences Research Laboratories, University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX
United Kingdom

  • Review Article
    Obesity and Type 2 Diabetes Mellitus
    Author(s): Saboor Aftab SA, Reddy N, Smith E and Barber TMSaboor Aftab SA, Reddy N, Smith E and Barber TM

    The global obesity epidemic is showing no signs of abating, and is fuelling an explosion in numbers of Type 2 Diabetes Mellitus (T2D) worldwide. Despite clear epidemiological and pathophysiological links between obesity and T2D, the actual mechanisms are complex given that some people with obesity appear to be protected in some way from developing T2D, and T2D can develop in a minority of lean people. Obesity and T2D form part of the metabolic syndrome, which combined with hypertension and dyslipidaemia result in premature mortality from cardiovascular disease in millions of people globally each year. Long-term microvascular sequelae from T2D and multiple co-morbidities associated with obesity (including psychological, musculoskeletal, respiratory and reproductive) also have a major adverse impact on quality of life and pose an enormous fiscal burden on global health authorities. Majo.. Read More»
    DOI: 10.4172/2165-8048.S6-002

    Abstract PDF

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