Internal Medicine: Open Access
Open Access
ISSN: 2165-8048
+44 1300 500008
ISSN: 2165-8048
+44 1300 500008
Amal Zaghloul
Makkah
Saudi Arabia
Research Article
Thrombosis in Hemodialysis Patients; Their Association with Tissue Factor and Tissue Factor Pathway Inhibitor
Author(s): Amal Zaghloul, Talat Bukhari, Nada Bajuaifer, Maged Shalaby, Hamed Pakistani, Saeed Halawani and Shirin TeamaAmal Zaghloul, Talat Bukhari, Nada Bajuaifer, Maged Shalaby, Hamed Pakistani, Saeed Halawani and Shirin Teama
Background: Thrombotic complications are common in patients undergoing maintenance hemodialysis.
The aim of the study: to measure tissue factor (TF) and tissue factor pathway inhibitor (TFPI) levels in hemodialysis patients and to elucidate their role with thrombotic episodes.
Methods: 61 patients on hemodialysis as well as 19 healthy persons were included. The patients were reclassified into high and low groups according to the 90th and 10th percentile of controls of both TF and TFPI respectively to predict if higher than the 90th percentile of TF or lower than 10th percentile of TFPI were associated with thrombotic complications or not. All participants subjected to complete hemogram, measurement of TF and TFPI by enzyme linked immunosorbent assay.
Results: TF and TFPI were significantl.. View More»
DOI:
10.4172/2165-8048.1000183