Drug Designing: Open Access
Open Access

A Review of the Development of Calcium Pterins and (250:1 Mol:Mol) Calcium Folate for the Immunotherapy of Certain Diseases

Phillip B. Berkey Moheno

DOI: 10.4172/2169-0138.1000140

Repurposing of Modified Alpidem and Propoxyphene to Cure AURKA, BCAS1, GNAS and MLH1 Gene Mutations in Colorectal Cancer

Anum Munir, Shumaila Azam, Sartaj Ali, Azhar Mehmood, Abbas Hussain Shah, M Saad Khan, Rabbiah Manzoor, Maria Sana, Shakeel Ahmed Mufti and Sahar Fazal

DOI: 10.4172/2169-0138.1000141

An Integrated Computational and Experimental Binding Study Identifies the DNA Binding Domain as the Putative Binding Site of Novel Pyrimidinetrione Signal Transducer and Activator of Transcription 3 (STAT3) Inhibitors

Shan Sun, Peibin Yue, Mingzhu He, Xiaolei Zhang, David Paladino, Yousef Al-Abed, James Turkson and John K Buolamwini

DOI: 10.4172/2169-0138.1000142

Synthesis, Biological Evaluation and Modeling Studies of New Pyrido[3,4-b] indole Derivatives as Broad-Spectrum Potent Anticancer Agents

Shivaputra A Patil, James K Addo, Hemantkumar Deokar, Shan Sun, Jin Wang, Wei Li, D Parker Suttle, Wei Wang, Ruiwen Zhang and John K Buolamwini

New Potential In Situ Anticancer Agent Derived from [¹⁸⁸Re]rhenium Nitro-Imidazole Ligand Loaded 5th Generation Poly-L-Lysine Dendrimer for Treatment of Transplanted Human Liver Carcinoma in Nude Mice

Guanghua Yang, Nouredine Sadeg and Hafid Belhadj-Tahar

DOI: 10.4172/2169-0138.1000144

Efficacy or Exaggeration The Likely Role of Evefresh Cream for SLE

Aruna V, Soundharya R and Gayathri R

DOI: 10.4172/2169-0138.1000145

Homology Modeling of Human Concentrative Nucleoside Transporters (hCNTs) and Validation by Virtual Screening and Experimental Testing to Identify Novel hCNT1 Inhibitors

Hemant Kumar Deokar, Hilaire Playa and John K Buolamwini

DOI: 10.4172/2169-0138.1000146