Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Abstract

Treatment of Cogan?s Syndrome during Pregnancy with Off-Label Application of Intravenous Immunoglobulins (IVIG)

Thorsten Krieger*, Friedrich Haag, Felix Scherg

We report the case of a woman with Cogan’s syndrome and the desire for pregnancy. After three major flares leading to unilateral deafness, immunosuppressive therapy with prednisolone and azathioprine was started. Because of severe side effects, an off-label therapy with Intravenous Immunoglobulins (IVIG) was initiated, under which the patient has given birth to three healthy children. To our knowledge this is the first report to describe Cogan’s syndrome with multiple successful pregnancies under IVIG treatment.

Published Date: 2025-04-19; Received Date: 2024-08-17