Oreochromis niloticus species are adapted to their own set of local ecological and climatic conditions from the Paisuni river, India. Consequently, environmental conditions and their connectivity to organisms may play a big role in generating growth outcome of non-native species in natural conditions. Study was undertaken during the period of October 2015 to September 2016 from the Paisuni river, India. Invasive potential of O. niloticus was measured through size composition, age and growth from the Paisuni river. The total length of fishes varied from 96 to 398 mm with 0+ to 6+ age groups. Their size groups and age groups indicated that the O. niloticus are well stable in the Paisuni river. Their stock and density from the Paisuni river are helping to fisher community for their livelihood and malnutrition as well as poor men malnutrition. The maximum growth increment was observed in 1+ age group (145 mm) and minimum in 6+ age groups (14 mm). The growth of fishes very systematically declined after 1+ age group in the Paisuni river. The maximum fishes were exploited in 241 to 270 mm size group with 18.39%. These sizes of fishes are very attract and magnetize to the fishers from the Paisuni river.