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This perspective appraises the pathology, etiology, clinical presentation and therapy of osteoporosis, and focuses on implications for oral healthcare. Osteoporosis is a chronic insidious, debilitating disease of aging, slowly affecting the quality of life of both genders. Very few people show no signs of OP as they age. A healthy balanced diet, rich in calcium combined with daily rigorous exercise seems to be the sole natural formula for retarding OP. Osteonecrosis of the Jaws (ONJ) is a rare complication and precise management is unresolved; management is by prevention of ONJ, is feasible mainly by completing all invasive dentistry before prescribing bisphosphonates.