Ovarian cancer is the most lethal gynecological malignancy in the industrialized countries and is characterized by an intraperitoneal spread involving the wall of the large bowel from serosa. Rarely, both at the time of diagnosis and in recurrences, neoplastic metastasis to colon and rectum spread through vessels presenting as an intraluminal masses that involve mucosa and submucosa and mimic a primitive colonic cancer. In this case report, we present a case of a 49-year-old patient that showed irregular bowel motion alternating diarrhea and constipation, after ten months from the first surgery with complete cytoreduction for ovarian cancer. Primitive cancer was a mixed high-grade epithelial adenocarcinoma, clear cell and serous, FIGO staging IIB. Colonoscopy showed an intraluminal fungating mass of about 3 cm at 7 cm from the anal verge, with macroscopic aspect suggesting a primitive colonic cancer. A biopsy was performed, and the diagnosis was consistent with recurrence of ovarian adenocarcinoma. No serosal infiltration was present. The patient was treated with left hemicolectomy. Furthermore, we reviewed the literature about other cases of intraluminal colonic recurrence and articles about differential diagnosis between primitive cancer of colon and rectum and metastasis/recurrence from ovarian cancer.
Published Date: 2022-03-11; Received Date: 2022-01-30