Journal of Clinical and Experimental Ophthalmology
Open Access

Abstract

Correlations of Primary Angle Closure Glaucoma Susceptibility Gene and Ocular Biometry

Haihong Shi and Huaijin Guan

Specific anatomic features are risk factors for primary angle closure glaucoma (PACG), a dominant type of glaucoma in Asia. Some tissue remodeling genes have been reported associated with PACG. A Genome-wide association study identified three new susceptibility loci for PACG. However, the exact mechanism of these genes in PACG pathogenesis is still unclear. This commentary summarized the correlations of PACG susceptibility genes and ocular biometry and may help to understand the pathology of PACG better.