Purpose: To evaluate the association among age, gender, central corneal thickness (CCT), anterior chamber depth (ACD) and higher-order aberrations (HOAs) of cornea in Chinese people with emmetropia by Pentacam.
Methods: Prospective, a non-randomized population-based study. All subjects came spontaneously for consultation and were subdivided into six age-groups. One thousand two hundred and six candidates (605 male, 601 female) were tested and underwent Anterior segment examination by Pentacam. These parameters were measured: 1) root mean square-HOA (RMS-HOA) from anterior and posterior cornea, 2) RMS of coma, secondary astigmatism and spherical aberration (SA) from anterior and posterior cornea, 3) CCT and ACD.
Results: For analysis of variance (ANOVA) between genders, there were statistical differences on: 1) anterior corneal HOAs of x-coma, y-coma and SA (F=5.643, P=0.018; F= 16.971, P=0.000; F=23.443, P=0.000); 2) total corneal HOAs of y-coma and SA (F=12.906, P=0.000; F=111.590, P=0.000). There was significant different between y-second astigmatism of anterior corneal surface and age (r2 =0.023, p<0.000), that of posterior corneal surface and age (r2 =0.021, p=0.001), between RMS-HOAs of anterior corneal surface and age (r2 =0.259, p<0.000), that of posterior corneal surface and age (r2 =0.055, p=0.001), that of total corneal surface and age (r2 =0.359, p<0.000).
Conclusion: a) For the ethnic, there was a significant difference on magnitude of corneal HOAs between Chinese people and the other people. b) Pentacam can provide a more precise data of posterior cornea HOAs which seldom reported before.