Current Synthetic and Systems Biology
Open Access

Brian Brown

Biography

Brian Brown is broadly trained in molecular and cellular biology with a strong focus on immunology and translational medicine. His training began with his doctoral studies in Canada and his work with hematologist Dr. David Lillicrap and virologist Dr. Frank Graham to establish ways to overcome the immune response hindering gene therapy. He subsequently did his postdoctoral studies in Italy under the supervision of Drs. Luigi Naldini and Maria Grazia Roncarolo, leaders in molecular medicine and immunology. There, he helped develop a new platform for controlling gene expression, which has led to improvements in experimental treatments for genetic disease, cancer, and viral infection. In 2008 Dr. Brown joined the faculty of Mount Sinai as an Assistant Professor and he was promoted to Associate Professor in 2013.

Research Interest

Antigen Presentation, Autoimmunity Cell Biology, Cellular Immunity, Dendritic Cells, Diabetes, Gene Discovery, Gene Expressions, Gene Regulation, Gene Therapy, Immunological Tolerance, Immunology Infectious Disease Inflammation, Macrophage, Molecular Biology, RNA, RNA Splicing & Processing, Retrovirus, T Cells, Tolerance Transcriptional Activation and Repression, Transgenic Mice.