The potential of metabolomics for natural product drug discovery | 1787
Biochemistry & Pharmacology: Open Access

Biochemistry & Pharmacology: Open Access
Open Access

ISSN: 2167-0501


The potential of metabolomics for natural product drug discovery as incorporated into broader

International Conference on Pharmacognosy, Phytochemistry & Natural Products

October 21-23, 2013 Radisson Blu Plaza Hotel, Hyderabad, India

Mohamed A. Farag

Accepted Abstracts: Biochem & Pharmacol

Abstract :

The ability to sequence whole plant and human genomes has taught us that our knowledge with respect to gene function is rather limited. Functional genomics analyses include investigations at the level of gene expression (transcriptomics), protein translation (proteomics) and more recently the metabolite network (metabolomics). Metabolomics is the study of global metabolite profiles in a system (cell, tissue, or organism) under a given set of conditions. The analysis of the metabolome is particularly challenging due to the diverse chemical nature of metabolites in a cell. This presentation provides an overview of metabolomics and discusses its complementary role within system biology. It highlights how metabolome analyses are being conducted using different spectroscopic techniques NMR and MS, and how the highly complex data generated are analyzed. Specific examples will then be presented to illustrate how metabolomics can lead to valuable information relative to natural products biosynthesis, herbal medicines quality control analysis and agricultural biotechnology.

Biography :

Specializing in plant metabolomics, Mohamed A. Farag completed his Ph.D. at Texas Tech University, USA, in 2003 and later worked as a postdoctoral fellow at The Samuel Noble Foundation, and the James Graham Brown Cancer Center, USA. Since 2009, Dr. Farag has been working as a visiting Professor at the Technical University of Munich, Germany, and in 2009?2010 he held Alexander von Humboldt fellowship. For his highly cited publications, he was recently elected to serve as an associate editor for Journal of Advanced Research. In 2011, he was selected as a top researcher in the field of plant biology in Africa by the American society of plant biology. He has published close to 40 in reputed journals with a total H-index of 15.