The impression of ubiquinone (coenzyme Q) in pharmacological and | 31227
Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

+44 1223 790975

The impression of ubiquinone (coenzyme Q) in pharmacological and clinical experiments

6th International Conference & Expo on Proteomics

March 29-31, 2016 Atlanta, USA

Du Qing

The Institute of Medicinal Plant Development, China

Scientific Tracks Abstracts: J Proteomics Bioinform

Abstract :

Ubiquinone(coenzyme Q) a kind of compound which can be classified into lipid soluble quinone from the structure. They differ from the number of isoprene located in the side chain of benzoquinone derivative. Till date, we know some research information about CoQ0, CoQ1, CoQ2, CoQ6,CoQ7,CoQ8, CoQ9,CoQ10 produced by the diverse biological creature or microzyme which has been found and varified by the international scientists. Coenzyme Q exists in three redox forms, fully oxidized (ubiquinone), semiquinone radical (ubisemiquinone) and fully reduced (ubiquinol). Therefore coenzyme Q can form micellar aggregates while working together in cell-free system, however, in the living cell, coenzyme can dissolve in lipid bilayers and can bound to proteins. Coenzyme Q is the center and an essential component of the mitochondrial electron transport chain. Coenzyme Q can closely combine with the protein in the respiratory chain to have the action from the intrisic mechanism. In general, CoQ9,CoQ10 has been extracted with the purified compound and CoQ10 has proven to have important functions through the pharmacological and clinical experiments. According to the research results and reports, CoQ10 has the potential ability to treat the diseases such as cardiovascular disease, Parkinson��?s disease and Huntington��?s disease. Scientists also pay more attention to the study on biosynthesis and metablism of coenzyme Q in order to seek the beneficial relationship between the precaution of diseases and function of coenzyme Q.

Biography :

Du Qing has completed her PhD in 2015 with major in Pharmacognosy from the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC) and Post-doctoral studies in the Institute of Genetics and Developmental Biology, Beijing, China before the end of 2015. She is a member of American Society of Plant Biologists and Chinese Society for Cell Biology. She is also a pharmacist and member of Chinese Pharmacist Association. She has published more than 5 papers in the BMC and Chinese famous journals.