Organic Chemistry: Current Research
Open Access
ISSN: 2161-0401
+44 1478 350008
ISSN: 2161-0401
+44 1478 350008
Nathaniel Weinstein
McGill University, Canada
Posters & Accepted Abstracts: Organic Chem Curr Res
Aim: Current literature on the association between periodontal disease and preterm birth remains inconclusive. The aim of this retrospective cohort study is to further analyse this relationship by comparing periodontal parameters among pregnant women who have delivered a full term baby with those who have delivered a preterm (<37 weeks GA) or very preterm (<32 weeks GA) baby. Methods: A retrospective cohort study was conducted using data collected for a previous multi-centre case-control study in Quebec, Canada. 49 pregnant women with periodontal disease and 196 periodontal healthy pregnant women were included in this study. Periodontal disease was defined using the Community Periodontal Index of Treatment Needs (CPITN) as a pocket depth â�?¥6 mm, with gingival bleeding at the same site. Preterm birth and very preterm birth were defined as gestational age <37 weeks and <32 weeks, respectively. Results: 9 of the 49 women with periodontal disease delivered preterm (18%), compared to 28 of the 196 women without periodontal disease (14%). Multivariable unconditional logistic regression was performed (OR: 1.35 [95% CI 0.59-3.09]). After adjusting for age, ethnicity, and income, the association remained insignificant (OR: 1.51 [95% CI 0.61-3.71]). Conclusion: Our findings do not support the hypothesis that periodontal disease is an independent risk factor for preterm birth or very preterm birth.