Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
ISSN: 2155-9880
Ahmed R Ahmed
University of Duisburg-Essen, Germany
Posters & Accepted Abstracts: J Clin Exp Cardiolog
Introduction: Ventricular assist devices (VADs) have been proven to be effective in improving survival and quality of life in patients with refractory heart failure. However, outcomes depend on a variety of pre-operative parameters. This study evaluates retrospectively patients��? profiles, clinical outcome, post-operative complications and mortality in patients who underwent VAD implantation in our center; taking into account pre-operative INTERMACS (The Interagency Registry for Mechanically Assisted Circulatory Support) levels. Methods: Between August 2010 and March 2015, 104 patients underwent VAD implantation in our university hospital. INTERMACS profiles were as follow: Level 1 in 27 patients, level 2 in 20 patients, level 3 in 27 patients, level 4 in 25 patients, level 5 in 4 patients and level 6 in 1 patient respectively. Patients were divided into 3 groups: Group A included 27 patients at INTERMACS level 1, group B included 47 patients at INTERMACS level 2/3 and group C included 30 patients at INTERMACS Level 4/5/6. Patients��? characteristics pre-VAD implant, incidence and time of onset of post-operative complications and mortality were compared between groups. Results: Sepsis was the most common post-operative complication after VAD implantation. Total mortality was higher in group A compared to group B (p=0.002) and group C (p=0.005), with no significant difference between groups B and C (p=0.902). Predictors of total mortality were pre-operative high CVP (p=0.008), high systolic PAP (p=0.007). Conclusion: INTERMACS scale correlates with outcome after VAD implantation in our single center study. Optimization of preoperative volume status, preload, right heart function is recommended to lower the total mortality in such patients.
Email: ahmed.ahmed@uk-essen.de