Drug Designing: Open Access
Open Access

Solid-state characterization of micophenolic acid

International Conference and Expo on Drug Discovery & Designing

August 11-13, 2015 Frankfurt, Germany

Ionut-Valentin Ledeti1, Gabriela Vlase1, Titus Vlase1, Lenuta-Maria Suta2, Ionel Ciucanu1 and Adriana Fulias2

Scientific Tracks Abstracts: Drug Des

Abstract :

Mycophenolic acid (MPH) is anbioactive compound, used as immunosuppressant agent employed in prevention of organ
transplant rejection in adults, but as well for renal transplant rejection in children with age over two years. Our study was
focused on the in-depth analysis of solid-state characterization of MPH, by the means of stability under ambient conditions and as
well under thermal stress. The samples were fully characterized using thermo analytical techniques (TG/DTG/HF), and as well FT-IR
spectroscopy. These results represent the preliminary information in carrying the complete kinetic analysis using iso-conversional
methods and NPK method.

Biography :

Ionu�?£ Lede�?£i has completed his from Politehnica University of Timi�?�?oara, and currently is a Postdoctoral student at West University of Timi�?�?oara, Romania. Up to the date,
he has published 53 papers in reputed journals, in the field of Physical Chemistry of Bioactive Substances.
This work was performed at West University of Timi�?�?oara and was supported by the strategic grant POSDRU/159/1.5/S/137750, Project “Doctoral and Postdoctoral
programs support for increased competitiveness in Exact Sciences research” cofinanced by the European Social Fund within the Sectorial Operational Programme Human
Resources Development 2007-2013” to Ionut Valentin Ledeti