Scientific Tracks Abstracts: JCEC
Older obese persons with decreased muscle mass or strength are at special risk for adverse outcomes. We discuss potential pathways to muscle impairment in obese individuals and the consequences that joint obesity and muscle impairment may have on health and disability. Excess energy intake, physical inactivity, low-grade inflammation, insulin resistance and changes in hormonal milieu may lead to the development of so called ?sarcopenic obesity?. It was originally believed that the culprit of age related muscle weakness was a reduction in muscle mass, but it is now clear that changes in muscle composition and quality are predominant. Recognition of obese patients who have associated muscle problems is an essential goal for clinicians. Further research is needed to identify new target for preventio n and cure of this important geriatric syndrome.