Journal of Developing Drugs

Journal of Developing Drugs
Open Access

ISSN: 2329-6631

+44 1478 350008

Posology in children oral liquid medication studies in Liberia

5th International Summit on GMP, GCP & Quality Control

August 12-13, 2016 Toronto, Canada

Kolawole J A, Paye P D and Smith K C

University of Liberia, Liberia

Posters & Accepted Abstracts: J Develop Drugs

Abstract :

Determination and implementation of appropriate dose(s) and dosing is important for therapeutic effectiveness of medications. This study surveyed children oral medications on the Liberian pharmaceutical market for appropriate dose/dosage and delivery devices. In the qualitative work, caregivers were interviewed and surveys were conducted in pharmacies for oral medications and the quantitative phase involved the evaluation of the delivery devices. The result of the survey showed that 95.7% of caregivers followed instructions provided at the point of dispensing or as on label of product. Survey result showed that 56% of the oral medicinal products have specific direction for usage while 73% have the inscription â�?�?as directed by the physicianâ�?, either alone or in combination with specific direction for use. Medicines with delivery device as cup were 80.94% and those with teaspoons were 1.79%, while 17.28% do not have any form of delivery device. 53.11% of the medicinal products provided instruction for delivery of the medicines in â�?�?teaspoonfulâ�?, though they did not contain teaspoon or cups graduated in â�?�?teaspoonfulâ�? format. Volume calibration of the teaspoons (n=12, Mean�?±SD; 5.389�?±1.219 ml) showed statistically significant difference (P<0.05), while the cups volume capacities at 5.0 ml was found to be 5.200�?±0.326 ml. The cups with volume capacities of 10.0 ml (64.89%) or above 10.0 ml (35.11%) were found to be susceptible to error as only 25.5% of the mothers were able to accurately measure out 5.0 ml in the cups and also showed significant difference (P<0.05) in the group.

Biography :

Kolawole J A, PhD, FPSN, FPCPharm, FIPAN, completed his PhD from the Ahmadu Bello University, Zaria and The Robert Gordon, University, Aberdeen, UK (1996). He is the Dean, Faculty of Pharmaceutical Sciences, University of Jos and Consultant to West African Health Organization, on development of guidelines and training manuals for, Pharmaceutical Finished Products; Pharmaceutical Raw Materials; Standard Operating Procedures for Laboratories; Bioavailability/ Bioequivalent. He has more than 40 publications in international journals.