Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
+44 1478 350008
ISSN: 2161-1017
+44 1478 350008
Anita Mani
Gift Gyno IVF Centre, India
Scientific Tracks Abstracts: Endocrinol Metab Syndr
PCOS is a chronic condition, affecting 3 to 20% population, of which 70% remains undiagnosed. Reproductive symptoms of PCOS are anovulation, sub fertility and hyperandrogenism. Metabolic disorders include glucose intolerance, type 2 Diabetes and CVD. Depression and anxiety are found in some patients. Life style changes including diet, exercise and weight loss should precede any pharmacological intervention. Even a 5% loss of body weight will reduce insulin resistance and circulating androgens, resulting in spontaneous ovulation and relief of symptoms. Behavior change techniques should target optimal weight. Protocols should be provided to clinicians, to assess CVD risks considering obesity, physical inactivity, smoking, dyslipidemia, hypertension, glucose intolerance and type II diabetes/family history. Clinicians should also look for sleep apnea symptoms. Pharmacological indications include gestogens to induce periods in severe oligomenorrhea patients to reduce risk of endometrial hyperplasia /cancer. Insulinsensitizing agents do not seem to have long-term benefits. Weight reduction drugs reduce hyper-androgenaemia in selected patients. Laparoscopic ovarian drilling will induce ovulation in 60% of the subjects for 20 years. When weight loss strategies fail, morbidly obese women can benefit from bariatric surgery. Psychological issues like depression and anxiety must be screened assessed and referred to professionals. Creating public health awareness on healthy eating and the necessity of regular exercise and including them in school curriculum is needed. A multidisciplinary approach involving atrained team of physicians, dieticians, exercise specialists and counselors is needed in long-term management of PCOS.
Anita Mani is a renowned infertility specialist in South India with 15 years experience in ART (Assisted Reproductive Technology). She completed MRCOG from Royal College of Obstetrician and gynecologist, London and worked in UK for 5 years. She believes in scientific and ethical practice and is currently the Director of Gift Gyno IVF Centre, Cochin and Bangalore. Apart from advanced laparoscopic surgeries, she is also an expert in various ART techniques including IVF, IUI and ICSI, donor egg / sperm and surrogacy. Her proficiency is in genetic abnormalities and high-risk pregnancies.
Email: anitadane@gmail.com