Nanoparticles versus modified plant protein as drug delivery vehi | 1829
Biochemistry & Pharmacology: Open Access

Biochemistry & Pharmacology: Open Access
Open Access

ISSN: 2167-0501

Nanoparticles versus modified plant protein as drug delivery vehicle

International Conference on Pharmacognosy, Phytochemistry & Natural Products

October 21-23, 2013 Radisson Blu Plaza Hotel, Hyderabad, India

S. Aradhana and V. Swarna Karthika

Accepted Abstracts: Biochem & Pharmacol

Abstract :

Nanotechnology is the emerging technology wherein everything is at the nanometer scale. Nano drug delivery systems have improved performance due to enhanced diffusion rate and high drug loading capacity so that it can be a controlled and targeted drug carrier. Though nano drug delivery vehicle has high specificity, it is very toxic mostly to brain as it may cross the blood brain barrier and can be easily recognized by white blood cells and hence cleared from circulation. To overcome this disadvantage, proteins from plants can be used as drug delivery carriers. Plant proteins are biocompatible and non-toxic. Modified plant proteins called oleosins from sunflower seeds tend to be biocompatible carriers for drug delivery. Proteins are genetically engineered to make a variety of protein molecules that assemble into vesicles for the purpose of drug delivery. Many proteins are being used as drug delivery carrier. But they have not been used as controlled drug delivery carrier. In case of recombinant proteins from sunflower seeds, they are capable of controlling the sequence of amino acids for targeting to specific receptors and other biological targets. In addition to the sunflower seeds protein being used as drug delivery carrier, they also have a protein ring sun flower trypsin Inhibitor (SFTI) which can be used in its natural form to block breast cancer enzymes. Thus plant proteins can be used as a vesicle as well as a drug for cancer treatment