Organic Chemistry: Current Research
Open Access
ISSN: 2161-0401
+44 1478 350008
ISSN: 2161-0401
+44 1478 350008
Pengcheng Xu and Xinxin Li
Shanghai Institute of Microsystem and Information Technology, China
Posters & Accepted Abstracts: Organic Chem Curr Res
For most of biochemical sensing applications, the ideal material are claimed to have multifunction such as the capability of molecular recognition, enrichment of analytes and anti-interference ability. To meet the multiple requirements, herein a novel nano-architecture with multi-dimension and highly favorable properties is hierarchical constructed from three nanoscale building blocks of graphene oxide (GO), ZnO nanowires and meal-organic frameworks (MOFs). To assemble the hierarchical nanostructure, one dimensional (1D) ZnO nanowires are firstly well-aligned grown on 2D GO nano-substrate to form a fuzzy-blanket-like nanostructure. The nanoporous ZIF-8 crystals (a subclass of MOFs) are subsequently grown on ZnO surface via a simple chemical vapor deposition (CVD) process. In the obtained nanoarchitectures, GO and ZnO components are two typical active nanomaterials for electrochemical-based biochemical sensors, while nanoporous ZIF-8 crystals material is suitable for biochemical molecules capturing/enriching. Having been tuned into electrochemical sensors, the nano-architectures constructed from GO, ZnO nanowires and ZIF-8 crystals exhibit ultra-high response to dopamine (DA), an important neurotransmitters in the mammalian central nervous system. The limit of detection (LOD) of obtained sensor is estimated as 0.5 nM which is the desired concentration limit for current applications. Furthermore, the integration of different active components shows considerable anti-interference ability towards four typical electroactive coexisting molecules of cysteine, glutathione, ascorbic acid and uric acid which indicates a good selectivity of the developed sensing material.
Email: xpc@mail.sim.ac.cn